Mary T. Didiuk: search on Z-Library

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1

Toxicophores, reactive metabolites and drug safety: when is it a cause for concern?

Kalgutkar, Amit S, Fate, Gwendolyn, Didiuk, Mary T, Bauman, Jonathan

Journal:

Expert Review of Clinical Pharmacology

Year:

2008

Language:

english

File:

PDF, 777 KB

english, 2008

2

Alkyl hydroperoxide oxidation of alkanes and alkenes with a highly active Mn catalyst.

Joseph E. Sarneski, Demetrius Michos, H. Holden Thorp, Mary Didiuk, Thomas Poon, Jennifer Blewitt, Gary W. Brudvig, Robert H. Crabtree

Journal:

Tetrahedron Letters

Year:

1991

Language:

english

File:

PDF, 215 KB

english, 1991

3

Pyrimidone-based series of glucokinase activators with alternative donor–acceptor motif

Filipski, Kevin J., Guzman-Perez, Angel, Bian, Jianwei, Perreault, Christian, Aspnes, Gary E., Didiuk, Mary T., Dow, Robert L., Hank, Richard F., Jones, Christopher S., Maguire, Robert J., Tu, Meihua,

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2013

Language:

english

File:

PDF, 3.33 MB

english, 2013

4

Zirconium-catalyzed ethylmagnesiation of hydroxylated terminal alkenes; a catalytic and diastereoselective carbon-carbon bond-forming reaction

Houri, Ahmad F., Didiuk, Mary T., Xu, Zhongmin, Horan, Nina R., Hoveyda, Amir H.

Journal:

Journal of the American Chemical Society

Year:

1993

Language:

english

File:

PDF, 1.40 MB

english, 1993

5

A novel series of glucagon receptor antagonists with reduced molecular weight and lipophilicity

Kevin J. Filipski, Jianwei Bian, David C. Ebner, Esther C.Y. Lee, Jian-Cheng Li, Matthew F. Sammons, Stephen W. Wright, Benjamin D. Stevens, Mary T. Didiuk, Meihua Tu, Christian Perreault, Janice Brow

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2012

Language:

english

File:

PDF, 830 KB

english, 2012

6

ChemInform Abstract: Structural Alerts, Reactive Metabolites, and Protein Covalent Binding: How Reliable Are these Attributes as Predictors of Drug Toxicity?

Amit S. Kalgutkar, Mary T. Didiuk

Journal:

Year:

2010

File:

PDF, 15 KB

2010

7

The design and synthesis of a potent glucagon receptor antagonist with favorable physicochemical and pharmacokinetic properties as a candidate for the treatment of type 2 diabetes mellitus

Guzman-Perez, Angel, Pfefferkorn, Jeffrey A., Lee, Esther C.Y., Stevens, Benjamin D., Aspnes, Gary E., Bian, Jianwei, Didiuk, Mary T., Filipski, Kevin J., Moore, Dianna, Perreault, Christian, Sammons,

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2013

Language:

english

File:

PDF, 1.48 MB

english, 2013

8

Formation of a high valent di-μ-oxo manganese dimer in aqueous solution

Rajesh Manchanda, Gary W. Brudvig, Robert H. Crabtree, Joseph E. Sarneski, Mary Didiuk

Journal:

Inorganica Chimica Acta

Year:

1993

Language:

english

File:

PDF, 291 KB

english, 1993

9

Zirconium-catalyzed asymmetric carbomagnesation

Morken, James P., Didiuk, Mary T., Hoveyda, Amir H.

Journal:

Journal of the American Chemical Society

Year:

1993

Language:

english

File:

PDF, 248 KB

english, 1993

10

ChemInform Abstract: Metal-Catalyzed Kinetic Resolution Processes

Amir H. Hoveyda, Mary T. Didiuk

Journal:

Year:

1999

File:

PDF, 24 KB

1999

11

A high-valent oxomanganese dimer containing bridging and terminal inorganic phosphate ligands

Sarneski, Joseph E., Didiuk, Mary., Thorp, H. Holden., Crabtree, Robert H., Brudvig, Gary W., Faller, J. W., Schulte, Gayle K.

Journal:

Inorganic Chemistry

Year:

1991

Language:

english

File:

PDF, 425 KB

english, 1991

12

Structural Alerts, Reactive Metabolites, and Protein Covalent Binding: How Reliable Are These Attributes as Predictors of Drug Toxicity?

Amit S. Kalgutkar, Mary T. Didiuk

Journal:

Chemistry & Biodiversity

Year:

2009

Language:

english

File:

PDF, 308 KB

english, 2009

13

The chemistry of high-valent oxomanganese clusters in aqueous solution: A (IV,IV) dimer containing bridging and terminal phosphate ligands

Joseph E. Sarneski, Mary Didiuk, H.Holden Thorp, Robert H. Crabtree, Gary W. Brudvig, J.W. Faller, Gayle K. Schulte

Journal:

Journal of Inorganic Biochemistry

Year:

1991

Language:

english

File:

PDF, 95 KB

english, 1991

14

Short-acting 5-(trifluoromethyl)pyrido[4,3-d]pyrimidin-4(3H)-one derivatives as orally-active calcium-sensing receptor antagonists

Mary T. Didiuk, David A. Griffith, John W. Benbow, Kevin K.C. Liu, Daniel P. Walker, F. Christopher Bi, Joel Morris, Angel Guzman-Perez, Hua Gao, Bruce M. Bechle, Ryan M. Kelley, Xiaojing Yang, Kennet

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2009

Language:

english

File:

PDF, 2.01 MB

english, 2009

15

ChemInform Abstract: A Modular Synthetic Approach Toward Exhaustively Stereodiversified Ligand Libraries.

Tiffany Malinky Gierasch, Milan Chytil, Mary T. Didiuk, Julie Y. Park, Jeffrey J. Urban, Steven P. Nolan, Gregory L. Verdine

Journal:

Year:

2001

File:

PDF, 25 KB

2001

16

Discovery Tactics To Mitigate Toxicity Risks Due to Reactive Metabolite Formation with 2-(2-Hydroxyaryl)-5-(trifluoromethyl)pyrido[4,3- d ]pyrimidin-4(3 H )-one Derivatives, Potent Calcium-Sensing Receptor Antagonists and Clinical Candidate(s) for the Treatment of Osteoporosis

Kalgutkar, Amit S., Griffith, David A., Ryder, Tim, Sun, Hao, Miao, Zhuang, Bauman, Jonathan N., Didiuk, Mary T., Frederick, Kosea S., Zhao, Sabrina X., Prakash, Chandra, Soglia, John R., Bagley, Scot

Journal:

Chemical Research in Toxicology

Year:

2010

Language:

english

File:

PDF, 427 KB

english, 2010

17

A Modular Synthetic Approach toward Exhaustively Stereodiversified Ligand Libraries

Gierasch, Tiffany Malinky, Chytil, Milan, Didiuk, Mary T., Park, Julie Y., Urban, Jeffrey J., Nolan, Steven P., Verdine, Gregory L.

Journal:

Organic Letters

Year:

2000

Language:

english

File:

PDF, 57 KB

english, 2000

18

Catalytic and Enantioselective Route to Medium-Ring Heterocycles. Asymmetric Zirconium-Catalyzed Ethylmagnesation of Seven- and Eight-Membered Rings

Visser, Michael S., Heron, Nicola M., Didiuk, Mary T., Sagal, John F., Hoveyda, Amir H.

Journal:

Journal of the American Chemical Society

Year:

1996

Language:

english

File:

PDF, 360 KB

english, 1996

19

Ni-Catalyzed Asymmetric Addition of Grignard Reagents to Unsaturated Cyclic Acetals. The Influence of Added Phosphine on Enantioselectivity

Gomez-Bengoa, Enrique, Heron, Nicola M., Didiuk, Mary T., Luchaco, Courtney A., Hoveyda, Amir H.

Journal:

Journal of the American Chemical Society

Year:

1998

File:

PDF, 474 KB

1998

20

Directed Regio- and Stereoselective Nickel-Catalyzed Addition of Alkyl Grignard Reagents to Allylic Ethers

Didiuk, Mary T., Morken, James P., Hoveyda, Amir H.

Journal:

Journal of the American Chemical Society

Year:

1995

Language:

english

File:

PDF, 268 KB

english, 1995

21

Exploring Aromatic Chemical Space with NEAT: Novel and Electronically Equivalent Aromatic Template

Tu, Meihua, Rai, Brajesh K., Mathiowetz, Alan M., Didiuk, Mary, Pfefferkorn, Jeffrey A., Guzman-Perez, Angel, Benbow, John, Guimarães, Cristiano R. W., Mente, Scot, Hayward, Matthew M., Liras, Spiros

Journal:

Journal of Chemical Information and Modeling

Year:

2012

Language:

english

File:

PDF, 526 KB

english, 2012

22

Enantio-, Diastereo-, and Regioselective Zirconium-Catalyzed Carbomagnesation of Cyclic Ethers with Higher Alkyls of Magnesium. Utility in Synthesis and Mechanistic Implications

Didiuk, Mary T., Johannes, Charles W., Morken, James P., Hoveyda, Amir H.

Journal:

Journal of the American Chemical Society

Year:

1995

Language:

english

File:

PDF, 889 KB

english, 1995

23

Zirconium-Catalyzed Kinetic Resolution of Pyrans

Morken, James P., Didiuk, Mary T., Visser, Michael S., Hoveyda, Amir H.

Journal:

Journal of the American Chemical Society

Year:

1994

Language:

english

File:

PDF, 237 KB

english, 1994

24

Directed regioselective Ni-catalyzed alkylation and hydride addition of allylic ethers. A remarkable turnover in regioselectivity

James P. Morken, Mary T. Didiuk, Amir H. Hoveyda

Journal:

Tetrahedron Letters

Year:

1996

Language:

english

File:

PDF, 260 KB

english, 1996

25

Phosphine-directed stereo- & regioselective Ni-catalyzed reactions of Grignard reagents with allylic ethers

Mary T. Didiuk, James P. Morken, Amir H. Hoveyda

Journal:

Year:

1998

Language:

english

File:

PDF, 813 KB

english, 1998

26

A study of high-valent manganese in aqueous phosphoric acid: disproportionation of the bis(.mu.-oxo)dimanganese(III,IV) bipyridine complex [MnIIIMnIV(.mu.-O)2(bpy)4]3+

Sarneski, Joseph E., Brzezinski, Linda J., Anderson, Brandon, Didiuk, Mary, Manchanda, Rajesh, Crabtree, Robert H., Brudvig, Gary W., Schulte, Gayle K.

Journal:

Inorganic Chemistry

Year:

1993

Language:

english

File:

PDF, 685 KB

english, 1993

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